Eat less, exercise more. You’ve probably heard that’s the secret to weight loss. So, it makes sense that if you want to lose weight quickly, or if you’ve hit a weight-loss plateau, you need to really ramp up the exercise, right? Unfortunately, many people experience frustration with this approach. Why aren’t they successful? Research suggests that weight loss can be more complex than a simple “calories in/calories out” formula. In fact, our hormones play a larger role in regulating our metabolism than many people realize.